A-BEACON – AI Detection and Segmentation of Brain Metastases<\/title>\n \n \n <meta name=\"description\" content=\"The A-BEACON project develops an innovative AI system for 'zero-miss' detection and segmentation of brain metastases. A multicentric collaboration between Switzerland, Romania, Poland, and Bulgaria.\">\n <meta name=\"keywords\" content=\"A-BEACON, brain metastases, AI, tumor segmentation, neuro-oncology, ACTTA, medical research, ULBS, Swiss Contribution\">\n <meta name=\"author\" content=\"A-BEACON Team\">\n <link rel=\"canonical\" href=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/en\/\">\n \n \n <meta property=\"og:title\" content=\"A-BEACON - Innovation in Brain Metastasis Detection\">\n <meta property=\"og:description\" content=\"AI system for 'zero-miss' detection and tracking of brain metastases. 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\n color: white;\n z-index: 10;\n }\n\n \/* Large Hero Title on Two Lines *\/\n .hero-title-large {\n font-size: 3.5rem;\n font-weight: 800;\n line-height: 1.1;\n margin-bottom: 1.5rem;\n max-width: 900px;\n text-shadow: 2px 2px 4px rgba(0,0,0,0.7);\n }\n\n @media (max-width: 768px) {\n .hero-title-large {\n font-size: 2.5rem;\n }\n .hero-text-overlay {\n padding: 1.5rem;\n }\n }\n\n \/* Flags *\/\n .flag-icon {\n font-size: 1.2rem;\n line-height: 1;\n cursor: pointer;\n transition: transform 0.2s;\n }\n .flag-icon:hover {\n transform: scale(1.2);\n }\n .flag-active {\n border-bottom: 2px solid #2563eb;\n padding-bottom: 2px;\n }\n\n \/* Specific Styles *\/\n h2 {\n color: #1e293b;\n border-left: 4px solid #2563eb;\n padding-left: 1rem;\n margin-bottom: 1.5rem;\n }\n\n \/* Smooth scroll behavior *\/\n html {\n scroll-behavior: smooth;\n }\n <\/style>\n<\/head>\n<body>\n\n<div id=\"abeacon-content\">\n\n \n <div class=\"internal-nav px-4 shadow-sm\">\n <div class=\"flex flex-col md:flex-row justify-between items-center max-w-6xl mx-auto\">\n <div class=\"flex flex-wrap justify-center md:justify-start gap-4 mb-2 md:mb-0\">\n <a href=\"#about\">About project<\/a>\n <a href=\"#stages\">Stages<\/a>\n <a href=\"#consortium\">Consortium<\/a>\n <a href=\"#team\">Team<\/a>\n <\/div>\n \n <div class=\"flex gap-4 items-center\">\n <a href=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/\" class=\"flag-icon opacity-70 hover:opacity-100\" title=\"Rom\u00e2n\u0103\">\ud83c\uddf7\ud83c\uddf4<\/a>\n <span class=\"flag-icon flag-active\" title=\"English\">\ud83c\uddec\ud83c\udde7<\/span>\n <a href=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/a-beaconfr\/\" class=\"flag-icon opacity-70 hover:opacity-100\" title=\"Fran\u00e7ais\">\ud83c\uddeb\ud83c\uddf7<\/a>\n <\/div>\n <\/div>\n <\/div>\n\n \n <div class=\"px-4\">\n <div class=\"hero-banner max-w-6xl mx-auto\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/hero_site-scaled.png\" alt=\"Brain MRI Analysis\" class=\"hero-img\">\n <div class=\"hero-text-overlay\">\n \n <h1 class=\"hero-title-large\">\n AI Detection and Segmentation<br>\n of Brain Metastases\n <\/h1>\n <p class=\"text-xl font-light opacity-90 mb-8 border-l-4 border-blue-400 pl-4 bg-black\/20 p-2 inline-block rounded backdrop-blur-sm\">\n Project A-BEACON (230215)\n <\/p>\n <a href=\"#about\" class=\"bg-blue-600 hover:bg-blue-700 text-white font-semibold py-3 px-8 rounded shadow-lg transition transform hover:-translate-y-0.5 text-lg inline-block\">Learn more<\/a>\n <\/div>\n <\/div>\n <\/div>\n\n \n <section id=\"about\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold\">About the project<\/h2>\n <div class=\"prose prose-slate max-w-none text-justify bg-white p-6 rounded-lg shadow-sm border border-slate-100\">\n <p class=\"mb-4\">\n Brain metastases are the most prevalent brain neoplasms, affecting one in five adult cancer patients and accounting for more than half of all intracranial tumors in adults. Early detection and diagnosis are crucial, as untreated lesions can lead to delayed treatment, severe neurological deficits, and reduced overall survival.\n <\/p>\n <p class=\"mb-4\">\n Current diagnosis and treatment planning rely heavily on Magnetic Resonance Imaging (MRI), which is labor-intensive and error-prone, particularly in the manual segmentation and tracking of small and numerous lesions. Manual segmentation of brain metastases from MRI scans is time-consuming, with significant variability and sensitivity issues, often leading to missed lesions. There is a critical unmet need for more efficient, accurate, and reliable methods to assist clinicians in diagnosing and monitoring these tumors. To date, no effective solution is available for physicians.\n <\/p>\n <p class=\"mb-4\">\n Recent advances in Artificial Intelligence (AI) have shown promise in addressing these challenges. AI-based models have improved the segmentation and detection of brain metastases. However, variability in MRI protocols, data quality, and model generalization remain significant hurdles.\n <\/p>\n \n <div class=\"mt-8 p-4 bg-blue-50 rounded border-l-4 border-blue-600\">\n <h3 class=\"font-bold text-blue-900 text-lg mb-2\">Innovative Approach – A-BEACON Framework<\/h3>\n <p class=\"text-sm text-blue-900\">\n We propose the development of A-BEACON, an AI-based system designed to offer „zero-miss” detection and efficient tracking of brain metastases. Our approach proposes innovative AI methodologies and strategies for Active Test-Time Augmentation (ACTTA) and interpretability-based inductive biases to boost model performance and reliability.\n Using a multicentric dataset of 914 re-annotated cases, we will train and validate our models. This dataset, selected for its diversity in terms of imaging characteristics and lesion profiles, will form the backbone of our research.\n <\/p>\n <\/div>\n\n \n <div class=\"grid md:grid-cols-2 gap-6 mt-8\">\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Active Test-Time Augmentation (ACTTA)<\/h4>\n <p class=\"text-sm text-slate-700\">This novel technique will optimize test-time augmentation based on user corrections, improving model adaptability and performance without requiring retraining.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Interpretability-Based Inductive Bias<\/h4>\n <p class=\"text-sm text-slate-700\">By incorporating saliency maps to guide model training, this method aims to enhance detection capabilities by aligning model features with human expert knowledge.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Lesion Tracking<\/h4>\n <p class=\"text-sm text-slate-700\">By combining epistemic and aleatoric uncertainties, we will develop methods to track lesions over time, differentiating new metastases from existing ones.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Software Integration (TRL-4-5)<\/h4>\n <p class=\"text-sm text-slate-700\">A prototype software tool will be developed to integrate these technologies, enabling clinical deployment and evaluations.<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n \n <section id=\"stages\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold\">Implementation Stages<\/h2>\n <div class=\"space-y-6\">\n \n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Year 1 (Months 1-12)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Initiation<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Project launch and recruitment of the research team.<\/li>\n <li>Acquisition and installation of necessary equipment.<\/li>\n <li>Patient recruitment and clinical workshops for protocol specification.<\/li>\n <li>Dataset preparation: Switzerland (n=200), Romania (n=150), Poland (n=150).<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Year 2 (Months 13-24)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Technical Dev<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Development of base AI models for segmentation (cross-validation benchmark).<\/li>\n <li>Development of interpretability-based encoder and TTA variants.<\/li>\n <li>Development of the <strong>ACTTA (Active Test-Time Augmentation)<\/strong> framework.<\/li>\n <li>Development of A-BEACON v1.0 software tool and tracking module.<\/li>\n <li>Preliminary clinical evaluation (human-in-the-loop).<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Year 3 (Months 25-36)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Multicentric Eval<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Advanced technical evaluation of the tracking algorithm.<\/li>\n <li>Advanced radiomics analysis to evaluate tumor heterogeneity.<\/li>\n <li>Multicentric clinical evaluations \u2013 Round 1 (Switzerland) and Round 2 (Romania).<\/li>\n <li>Technical publications on the ACTTA framework and technical performance.<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Year 4 (Months 37-48)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Final Validation<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Multicentric clinical evaluations \u2013 Round 3 (Poland and Bulgaria).<\/li>\n <li>Finalization of analyses and final clinical validation of the A-BEACON system.<\/li>\n <li>Preparation and publication of final clinical and technical results.<\/li>\n <li>Final release of A-BEACON software to the scientific community.<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n <\/div>\n <\/section>\n\n \n <section id=\"consortium\" class=\"mb-16 px-4 max-w-6xl mx-auto bg-white py-8 rounded-lg shadow-sm border border-slate-100 pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold text-center mb-8\">International Consortium<\/h2>\n <div class=\"grid grid-cols-1 sm:grid-cols-2 lg:grid-cols-4 gap-6 px-4\">\n \n <a href=\"https:\/\/www.unibe.ch\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\udde8\ud83c\udded<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">University of Bern<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Project Leader<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.ulbsibiu.ro\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border-b-4 border-blue-600 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\uddf7\ud83c\uddf4<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">Lucian Blaga University of Sibiu<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Clinical & Technical Partner<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.pib-nio.pl\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\uddf5\ud83c\uddf1<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">National Research Institute of Oncology<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Oncology Expertise<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.mu-varna.bg\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\udde7\ud83c\uddec<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">Medical University Varna<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Clinical Evaluation<\/p>\n <\/a>\n <\/div>\n <\/section>\n\n \n <section id=\"team\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold mb-8\">Research Team<\/h2>\n \n <div class=\"grid grid-cols-1 sm:grid-cols-2 md:grid-cols-4 gap-8 mb-12\">\n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/mauricio.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Mauricio+Reyes&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Mauricio Reyes\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Mauricio Reyes<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Main Applicant (CH)<\/p>\n <\/div>\n \n <div class=\"text-center p-2 bg-blue-50\/30 rounded-xl border border-blue-100 group\">\n <div class=\"w-40 h-40 bg-white mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/matei.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Claudiu+Matei&background=fff&size=256'\" alt=\"Prof. Dr. Claudiu Matei\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Claudiu Matei<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Project Manager (RO)<\/p>\n <\/div>\n \n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/kunicki.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Jacek+Kunicki&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Jacek Kunicki\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Jacek Kunicki<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Investigator (PL)<\/p>\n <\/div>\n \n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/encheva.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Elitsa+Encheva&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Elitsa Encheva\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Elitsa Encheva<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Investigator (BG)<\/p>\n <\/div>\n <\/div>\n\n <div class=\"border-t border-slate-200 pt-8\">\n <h3 class=\"text-sm font-bold text-slate-500 mb-8 text-center uppercase tracking-widest\">ULBS Team (Romania)<\/h3>\n <div class=\"flex flex-wrap justify-center gap-10\">\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/neamtu.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Bogdan+Neamtu&background=f1f5f9&size=256'\" alt=\"Assoc. Prof. Dr. Bogdan Neam\u021bu\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Assoc. Prof. Dr. Bogdan Neam\u021bu<\/p>\n <p class=\"text-xs text-slate-500\">Senior Researcher<\/p>\n <\/div>\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/sandu.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Mariana+Sandu&background=f1f5f9&size=256'\" alt=\"Dr. Mariana Sandu\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Dr. Mariana Sandu<\/p>\n <p class=\"text-xs text-slate-500\">Researcher<\/p>\n <\/div>\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/darius.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Darius+Peteleaza&background=f1f5f9&size=256'\" alt=\"Eng. Darius Peteleaz\u0103\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Eng. Darius Peteleaz\u0103<\/p>\n <p class=\"text-xs text-slate-500\">Research Assistant<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n \n <footer class=\"bg-slate-800 text-slate-300 py-10 px-4 text-center mt-12 rounded-t-lg mx-auto max-w-6xl\">\n <div class=\"max-w-2xl mx-auto\">\n <p class=\"text-sm mb-4\">This project aims to significantly improve the standard of care for patients with brain metastases.<\/p>\n <p class=\"text-sm font-semibold mb-6\">Funded by the Swiss National Science Foundation (SNSF) and UEFISCDI.<\/p>\n <div class=\"w-16 h-px bg-slate-600 mx-auto mb-6\"><\/div>\n <div class=\"text-xs font-mono opacity-60\">\n © dr.ing. Radu Pascu – 2025.\n <\/div>\n <\/div>\n <\/footer>\n\n<\/div>\n\n<\/body>\n<\/html>\n","protected":false},"excerpt":{"rendered":"<p>A-BEACON – AI Detection and Segmentation of Brain Metastases About project Stages Consortium Team \ud83c\uddf7\ud83c\uddf4 \ud83c\uddec\ud83c\udde7 \ud83c\uddeb\ud83c\uddf7 AI Detection and Segmentation of Brain Metastases Project A-BEACON (230215) Learn more About the project Brain metastases are the most prevalent brain neoplasms, affecting one in five adult cancer patients and accounting for more than half of all […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-66","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/66","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/comments?post=66"}],"version-history":[{"count":5,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/66\/revisions"}],"predecessor-version":[{"id":90,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/66\/revisions\/90"}],"wp:attachment":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/media?parent=66"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

{"id":66,"date":"2025-12-11T11:23:54","date_gmt":"2025-12-11T09:23:54","guid":{"rendered":"https:\/\/grants.ulbsibiu.ro\/abeacon\/?page_id=66"},"modified":"2025-12-11T12:26:19","modified_gmt":"2025-12-11T10:26:19","slug":"a-beaconen","status":"publish","type":"page","link":"https:\/\/grants.ulbsibiu.ro\/abeacon\/a-beaconen\/","title":{"rendered":"A-BEACON(EN)"},"content":{"rendered":"\n\n\n\n \n \n A-BEACON – AI Detection and Segmentation of Brain Metastases<\/title>\n \n \n <meta name=\"description\" content=\"The A-BEACON project develops an innovative AI system for 'zero-miss' detection and segmentation of brain metastases. A multicentric collaboration between Switzerland, Romania, Poland, and Bulgaria.\">\n <meta name=\"keywords\" content=\"A-BEACON, brain metastases, AI, tumor segmentation, neuro-oncology, ACTTA, medical research, ULBS, Swiss Contribution\">\n <meta name=\"author\" content=\"A-BEACON Team\">\n <link rel=\"canonical\" href=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/en\/\">\n \n \n <meta property=\"og:title\" content=\"A-BEACON - Innovation in Brain Metastasis Detection\">\n <meta property=\"og:description\" content=\"AI system for 'zero-miss' detection and tracking of brain metastases. Funded by the Second Swiss Contribution.\">\n <meta property=\"og:type\" content=\"website\">\n <meta property=\"og:url\" content=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/en\/\">\n <meta property=\"og:image\" content=\"https:\/\/images.unsplash.com\/photo-1559757175-5700dde675bc?auto=format&fit=crop&q=80\">\n <meta property=\"og:locale\" content=\"en_US\">\n\n \n <meta name=\"twitter:card\" content=\"summary_large_image\">\n <meta name=\"twitter:title\" content=\"A-BEACON - AI Brain Metastasis Detection\">\n <meta name=\"twitter:description\" content=\"Innovative AI system for the detection and segmentation of brain metastases.\">\n <meta name=\"twitter:image\" content=\"https:\/\/images.unsplash.com\/photo-1559757175-5700dde675bc?auto=format&fit=crop&q=80\">\n \n \n <script src=\"https:\/\/cdn.tailwindcss.com\"><\/script>\n <link href=\"https:\/\/fonts.googleapis.com\/css2?family=Inter:wght@300;400;600;700;800&display=swap\" rel=\"stylesheet\">\n \n <style>\n \/* Hack to hide WordPress page title *\/\n .entry-title, .page-title, h1.entry-title {\n display: none !important;\n }\n\n body {\n background-color: #f8fafc;\n margin: 0;\n }\n\n #abeacon-content {\n font-family: 'Inter', sans-serif;\n color: #334155;\n line-height: 1.6;\n width: 100%;\n max-width: 100%; \n margin: 0 auto;\n background-color: #f8fafc;\n }\n \n .internal-nav {\n background: #ffffff;\n border-bottom: 1px solid #e2e8f0;\n padding: 1rem 0;\n margin-bottom: 2rem;\n position: sticky;\n top: 0;\n z-index: 40;\n }\n \n .internal-nav a {\n text-decoration: none;\n color: #475569;\n font-weight: 600;\n font-size: 0.9rem;\n margin-right: 1.5rem;\n transition: color 0.2s;\n }\n \n .internal-nav a:hover {\n color: #2563eb;\n }\n\n \/* Hero Banner Modified *\/\n .hero-banner {\n position: relative;\n width: 100%;\n height: 500px;\n border-radius: 8px;\n overflow: hidden;\n margin-bottom: 3rem;\n box-shadow: 0 4px 6px -1px rgba(0, 0, 0, 0.1);\n background-color: #1e293b; \/* Fallback color *\/\n }\n\n .hero-img {\n width: 100%;\n height: 100%;\n object-fit: cover;\n filter: blur(3px) brightness(0.6); \n transform: scale(1.02); \n transition: transform 0.5s ease;\n }\n \n .hero-banner:hover .hero-img {\n transform: scale(1.05);\n }\n\n .hero-text-overlay {\n position: absolute;\n top: 0;\n left: 0;\n width: 100%;\n height: 100%;\n display: flex;\n flex-direction: column;\n justify-content: center;\n align-items: flex-start;\n padding: 2rem 3rem; \n color: white;\n z-index: 10;\n }\n\n \/* Large Hero Title on Two Lines *\/\n .hero-title-large {\n font-size: 3.5rem;\n font-weight: 800;\n line-height: 1.1;\n margin-bottom: 1.5rem;\n max-width: 900px;\n text-shadow: 2px 2px 4px rgba(0,0,0,0.7);\n }\n\n @media (max-width: 768px) {\n .hero-title-large {\n font-size: 2.5rem;\n }\n .hero-text-overlay {\n padding: 1.5rem;\n }\n }\n\n \/* Flags *\/\n .flag-icon {\n font-size: 1.2rem;\n line-height: 1;\n cursor: pointer;\n transition: transform 0.2s;\n }\n .flag-icon:hover {\n transform: scale(1.2);\n }\n .flag-active {\n border-bottom: 2px solid #2563eb;\n padding-bottom: 2px;\n }\n\n \/* Specific Styles *\/\n h2 {\n color: #1e293b;\n border-left: 4px solid #2563eb;\n padding-left: 1rem;\n margin-bottom: 1.5rem;\n }\n\n \/* Smooth scroll behavior *\/\n html {\n scroll-behavior: smooth;\n }\n <\/style>\n<\/head>\n<body>\n\n<div id=\"abeacon-content\">\n\n \n <div class=\"internal-nav px-4 shadow-sm\">\n <div class=\"flex flex-col md:flex-row justify-between items-center max-w-6xl mx-auto\">\n <div class=\"flex flex-wrap justify-center md:justify-start gap-4 mb-2 md:mb-0\">\n <a href=\"#about\">About project<\/a>\n <a href=\"#stages\">Stages<\/a>\n <a href=\"#consortium\">Consortium<\/a>\n <a href=\"#team\">Team<\/a>\n <\/div>\n \n <div class=\"flex gap-4 items-center\">\n <a href=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/\" class=\"flag-icon opacity-70 hover:opacity-100\" title=\"Rom\u00e2n\u0103\">\ud83c\uddf7\ud83c\uddf4<\/a>\n <span class=\"flag-icon flag-active\" title=\"English\">\ud83c\uddec\ud83c\udde7<\/span>\n <a href=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/a-beaconfr\/\" class=\"flag-icon opacity-70 hover:opacity-100\" title=\"Fran\u00e7ais\">\ud83c\uddeb\ud83c\uddf7<\/a>\n <\/div>\n <\/div>\n <\/div>\n\n \n <div class=\"px-4\">\n <div class=\"hero-banner max-w-6xl mx-auto\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/hero_site-scaled.png\" alt=\"Brain MRI Analysis\" class=\"hero-img\">\n <div class=\"hero-text-overlay\">\n \n <h1 class=\"hero-title-large\">\n AI Detection and Segmentation<br>\n of Brain Metastases\n <\/h1>\n <p class=\"text-xl font-light opacity-90 mb-8 border-l-4 border-blue-400 pl-4 bg-black\/20 p-2 inline-block rounded backdrop-blur-sm\">\n Project A-BEACON (230215)\n <\/p>\n <a href=\"#about\" class=\"bg-blue-600 hover:bg-blue-700 text-white font-semibold py-3 px-8 rounded shadow-lg transition transform hover:-translate-y-0.5 text-lg inline-block\">Learn more<\/a>\n <\/div>\n <\/div>\n <\/div>\n\n \n <section id=\"about\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold\">About the project<\/h2>\n <div class=\"prose prose-slate max-w-none text-justify bg-white p-6 rounded-lg shadow-sm border border-slate-100\">\n <p class=\"mb-4\">\n Brain metastases are the most prevalent brain neoplasms, affecting one in five adult cancer patients and accounting for more than half of all intracranial tumors in adults. Early detection and diagnosis are crucial, as untreated lesions can lead to delayed treatment, severe neurological deficits, and reduced overall survival.\n <\/p>\n <p class=\"mb-4\">\n Current diagnosis and treatment planning rely heavily on Magnetic Resonance Imaging (MRI), which is labor-intensive and error-prone, particularly in the manual segmentation and tracking of small and numerous lesions. Manual segmentation of brain metastases from MRI scans is time-consuming, with significant variability and sensitivity issues, often leading to missed lesions. There is a critical unmet need for more efficient, accurate, and reliable methods to assist clinicians in diagnosing and monitoring these tumors. To date, no effective solution is available for physicians.\n <\/p>\n <p class=\"mb-4\">\n Recent advances in Artificial Intelligence (AI) have shown promise in addressing these challenges. AI-based models have improved the segmentation and detection of brain metastases. However, variability in MRI protocols, data quality, and model generalization remain significant hurdles.\n <\/p>\n \n <div class=\"mt-8 p-4 bg-blue-50 rounded border-l-4 border-blue-600\">\n <h3 class=\"font-bold text-blue-900 text-lg mb-2\">Innovative Approach – A-BEACON Framework<\/h3>\n <p class=\"text-sm text-blue-900\">\n We propose the development of A-BEACON, an AI-based system designed to offer „zero-miss” detection and efficient tracking of brain metastases. Our approach proposes innovative AI methodologies and strategies for Active Test-Time Augmentation (ACTTA) and interpretability-based inductive biases to boost model performance and reliability.\n Using a multicentric dataset of 914 re-annotated cases, we will train and validate our models. This dataset, selected for its diversity in terms of imaging characteristics and lesion profiles, will form the backbone of our research.\n <\/p>\n <\/div>\n\n \n <div class=\"grid md:grid-cols-2 gap-6 mt-8\">\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Active Test-Time Augmentation (ACTTA)<\/h4>\n <p class=\"text-sm text-slate-700\">This novel technique will optimize test-time augmentation based on user corrections, improving model adaptability and performance without requiring retraining.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Interpretability-Based Inductive Bias<\/h4>\n <p class=\"text-sm text-slate-700\">By incorporating saliency maps to guide model training, this method aims to enhance detection capabilities by aligning model features with human expert knowledge.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Lesion Tracking<\/h4>\n <p class=\"text-sm text-slate-700\">By combining epistemic and aleatoric uncertainties, we will develop methods to track lesions over time, differentiating new metastases from existing ones.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Software Integration (TRL-4-5)<\/h4>\n <p class=\"text-sm text-slate-700\">A prototype software tool will be developed to integrate these technologies, enabling clinical deployment and evaluations.<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n \n <section id=\"stages\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold\">Implementation Stages<\/h2>\n <div class=\"space-y-6\">\n \n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Year 1 (Months 1-12)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Initiation<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Project launch and recruitment of the research team.<\/li>\n <li>Acquisition and installation of necessary equipment.<\/li>\n <li>Patient recruitment and clinical workshops for protocol specification.<\/li>\n <li>Dataset preparation: Switzerland (n=200), Romania (n=150), Poland (n=150).<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Year 2 (Months 13-24)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Technical Dev<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Development of base AI models for segmentation (cross-validation benchmark).<\/li>\n <li>Development of interpretability-based encoder and TTA variants.<\/li>\n <li>Development of the <strong>ACTTA (Active Test-Time Augmentation)<\/strong> framework.<\/li>\n <li>Development of A-BEACON v1.0 software tool and tracking module.<\/li>\n <li>Preliminary clinical evaluation (human-in-the-loop).<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Year 3 (Months 25-36)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Multicentric Eval<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Advanced technical evaluation of the tracking algorithm.<\/li>\n <li>Advanced radiomics analysis to evaluate tumor heterogeneity.<\/li>\n <li>Multicentric clinical evaluations \u2013 Round 1 (Switzerland) and Round 2 (Romania).<\/li>\n <li>Technical publications on the ACTTA framework and technical performance.<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Year 4 (Months 37-48)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Final Validation<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Multicentric clinical evaluations \u2013 Round 3 (Poland and Bulgaria).<\/li>\n <li>Finalization of analyses and final clinical validation of the A-BEACON system.<\/li>\n <li>Preparation and publication of final clinical and technical results.<\/li>\n <li>Final release of A-BEACON software to the scientific community.<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n <\/div>\n <\/section>\n\n \n <section id=\"consortium\" class=\"mb-16 px-4 max-w-6xl mx-auto bg-white py-8 rounded-lg shadow-sm border border-slate-100 pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold text-center mb-8\">International Consortium<\/h2>\n <div class=\"grid grid-cols-1 sm:grid-cols-2 lg:grid-cols-4 gap-6 px-4\">\n \n <a href=\"https:\/\/www.unibe.ch\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\udde8\ud83c\udded<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">University of Bern<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Project Leader<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.ulbsibiu.ro\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border-b-4 border-blue-600 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\uddf7\ud83c\uddf4<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">Lucian Blaga University of Sibiu<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Clinical & Technical Partner<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.pib-nio.pl\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\uddf5\ud83c\uddf1<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">National Research Institute of Oncology<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Oncology Expertise<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.mu-varna.bg\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\udde7\ud83c\uddec<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">Medical University Varna<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Clinical Evaluation<\/p>\n <\/a>\n <\/div>\n <\/section>\n\n \n <section id=\"team\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold mb-8\">Research Team<\/h2>\n \n <div class=\"grid grid-cols-1 sm:grid-cols-2 md:grid-cols-4 gap-8 mb-12\">\n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/mauricio.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Mauricio+Reyes&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Mauricio Reyes\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Mauricio Reyes<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Main Applicant (CH)<\/p>\n <\/div>\n \n <div class=\"text-center p-2 bg-blue-50\/30 rounded-xl border border-blue-100 group\">\n <div class=\"w-40 h-40 bg-white mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/matei.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Claudiu+Matei&background=fff&size=256'\" alt=\"Prof. Dr. Claudiu Matei\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Claudiu Matei<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Project Manager (RO)<\/p>\n <\/div>\n \n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/kunicki.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Jacek+Kunicki&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Jacek Kunicki\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Jacek Kunicki<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Investigator (PL)<\/p>\n <\/div>\n \n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/encheva.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Elitsa+Encheva&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Elitsa Encheva\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Elitsa Encheva<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Investigator (BG)<\/p>\n <\/div>\n <\/div>\n\n <div class=\"border-t border-slate-200 pt-8\">\n <h3 class=\"text-sm font-bold text-slate-500 mb-8 text-center uppercase tracking-widest\">ULBS Team (Romania)<\/h3>\n <div class=\"flex flex-wrap justify-center gap-10\">\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/neamtu.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Bogdan+Neamtu&background=f1f5f9&size=256'\" alt=\"Assoc. Prof. Dr. Bogdan Neam\u021bu\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Assoc. Prof. Dr. Bogdan Neam\u021bu<\/p>\n <p class=\"text-xs text-slate-500\">Senior Researcher<\/p>\n <\/div>\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/sandu.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Mariana+Sandu&background=f1f5f9&size=256'\" alt=\"Dr. Mariana Sandu\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Dr. Mariana Sandu<\/p>\n <p class=\"text-xs text-slate-500\">Researcher<\/p>\n <\/div>\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/darius.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Darius+Peteleaza&background=f1f5f9&size=256'\" alt=\"Eng. Darius Peteleaz\u0103\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Eng. Darius Peteleaz\u0103<\/p>\n <p class=\"text-xs text-slate-500\">Research Assistant<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n \n <footer class=\"bg-slate-800 text-slate-300 py-10 px-4 text-center mt-12 rounded-t-lg mx-auto max-w-6xl\">\n <div class=\"max-w-2xl mx-auto\">\n <p class=\"text-sm mb-4\">This project aims to significantly improve the standard of care for patients with brain metastases.<\/p>\n <p class=\"text-sm font-semibold mb-6\">Funded by the Swiss National Science Foundation (SNSF) and UEFISCDI.<\/p>\n <div class=\"w-16 h-px bg-slate-600 mx-auto mb-6\"><\/div>\n <div class=\"text-xs font-mono opacity-60\">\n © dr.ing. Radu Pascu – 2025.\n <\/div>\n <\/div>\n <\/footer>\n\n<\/div>\n\n<\/body>\n<\/html>\n","protected":false},"excerpt":{"rendered":"<p>A-BEACON – AI Detection and Segmentation of Brain Metastases About project Stages Consortium Team \ud83c\uddf7\ud83c\uddf4 \ud83c\uddec\ud83c\udde7 \ud83c\uddeb\ud83c\uddf7 AI Detection and Segmentation of Brain Metastases Project A-BEACON (230215) Learn more About the project Brain metastases are the most prevalent brain neoplasms, affecting one in five adult cancer patients and accounting for more than half of all […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-66","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/66","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/comments?post=66"}],"version-history":[{"count":5,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/66\/revisions"}],"predecessor-version":[{"id":90,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/66\/revisions\/90"}],"wp:attachment":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/media?parent=66"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}