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Detectarea \u0219i diagnosticarea precoce sunt cruciale, deoarece leziunile netratate pot duce la \u00eent\u00e2rzierea tratamentului, deficite neurologice grave \u0219i reducerea supravie\u021buirii globale.\n <\/p>\n <p class=\"mb-4\">\n Diagnosticul actual \u0219i planificarea tratamentului se bazeaz\u0103 \u00een mare m\u0103sur\u0103 pe imagistica prin rezonan\u021b\u0103 magnetic\u0103 (IRM), care necesit\u0103 mult\u0103 munc\u0103 \u0219i este predispus\u0103 la erori, \u00een special \u00een segmentarea manual\u0103 \u0219i urm\u0103rirea leziunilor mici \u0219i numeroase. Segmentarea manual\u0103 a metastazelor cerebrale din scan\u0103rile RMN consum\u0103 mult timp, cu variabilitate semnificativ\u0103 \u0219i probleme de sensibilitate, ceea ce duce adesea la ratarea leziunilor. Exist\u0103 o nevoie critic\u0103 nesatisf\u0103cut\u0103 de metode mai eficiente, mai precise \u0219i mai fiabile pentru a asista medicii \u00een diagnosticarea \u0219i monitorizarea acestor tumori. P\u00e2n\u0103 \u00een prezent, nu exist\u0103 nicio solu\u021bie eficient\u0103 disponibil\u0103 pentru medici.\n <\/p>\n <p class=\"mb-4\">\n Progresele recente \u00een domeniul inteligen\u021bei artificiale (AI) s-au dovedit promi\u021b\u0103toare \u00een abordarea acestor provoc\u0103ri. Modelele bazate pe IA au \u00eembun\u0103t\u0103\u021bit segmentarea \u0219i detectarea metastazelor cerebrale. Cu toate acestea, variabilitatea protocoalelor RMN, calitatea datelor \u0219i generalizarea modelelor r\u0103m\u00e2n obstacole semnificative.\n <\/p>\n \n <div class=\"mt-8 p-4 bg-blue-50 rounded border-l-4 border-blue-600\">\n <h3 class=\"font-bold text-blue-900 text-lg mb-2\">Abordare inovatoare – Cadrul A-BEACON<\/h3>\n <p class=\"text-sm text-blue-900\">\n Propunem dezvoltarea A-BEACON, un sistem bazat pe inteligen\u021b\u0103 artificial\u0103 conceput pentru a oferi detectarea „zero-miss” \u0219i urm\u0103rirea eficient\u0103 a metastazelor cerebrale. Abordarea noastr\u0103 propune metodologii \u0219i strategii inovatoare de AI pentru augmentarea activ\u0103 \u00een timpul test\u0103rii (ACTTA) \u0219i bias-uri inductive bazate pe interpretabilitate pentru a spori performan\u021ba \u0219i fiabilitatea modelului.\n Utiliz\u00e2nd un set de date multicentric de 914 cazuri reanalizate, ne vom antrena \u0219i ne vom valida modelele. Acest set de date, selectat pentru diversitatea sa \u00een ceea ce prive\u0219te caracteristicile imagistice \u0219i profilurile leziunilor, va constitui coloana vertebral\u0103 a cercet\u0103rii noastre.\n <\/p>\n <\/div>\n\n \n <div class=\"grid md:grid-cols-2 gap-6 mt-8\">\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Active Test-Time Augmentation (ACTTA)<\/h4>\n <p class=\"text-sm text-slate-700\">Aceast\u0103 nou\u0103 tehnic\u0103 va optimiza augmentarea \u00een timpul test\u0103rii pe baza corec\u021biilor utilizatorului, \u00eembun\u0103t\u0103\u021bind adaptabilitatea \u0219i performan\u021ba modelului f\u0103r\u0103 a necesita reantrenare.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Interpretability-Based Inductive Bias<\/h4>\n <p class=\"text-sm text-slate-700\">Prin \u00eencorporarea h\u0103r\u021bilor de salien\u021b\u0103 pentru a ghida antrenarea modelului, aceast\u0103 metod\u0103 vizeaz\u0103 \u00eembun\u0103t\u0103\u021birea capacit\u0103\u021bilor de detectare prin alinierea caracteristicilor modelului cu cuno\u0219tin\u021bele exper\u021bilor umani.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Urm\u0103rirea leziunilor<\/h4>\n <p class=\"text-sm text-slate-700\">Prin combinarea incertitudinilor epistemice \u0219i aleatorii, vom dezvolta metode de urm\u0103rire a leziunilor \u00een timp, diferen\u021biind metastazele noi de cele existente.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Integrare software (TRL-4-5)<\/h4>\n <p class=\"text-sm text-slate-700\">Un prototip de instrument software va fi dezvoltat pentru a integra aceste tehnologii, permi\u021b\u00e2nd implementarea \u0219i evalu\u0103rile clinice.<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n \n <section id=\"etape\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold\">Etapele de implementare<\/h2>\n <div class=\"space-y-6\">\n \n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Anul 1 (Luni 1-12)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Ini\u021biere<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Lansarea proiectului \u0219i angajarea echipei de cercetare.<\/li>\n <li>Achizi\u021bionarea \u0219i instalarea echipamentelor necesare.<\/li>\n <li>Recrutarea pacien\u021bilor \u0219i workshop-uri clinice pentru specificarea protocoalelor.<\/li>\n <li>Preg\u0103tirea seturilor de date: Elve\u021bia (n=200), Rom\u00e2nia (n=150), Polonia (n=150).<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Anul 2 (Luni 13-24)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Dezvoltare Tehnic\u0103<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Dezvoltarea modelelor AI de baz\u0103 pentru segmentare (benchmark cross-validation).<\/li>\n <li>Dezvoltarea encoder-ului bazat pe interpretabilitate \u0219i a variantelor TTA (Test-Time Augmentation).<\/li>\n <li>Dezvoltarea cadrului <strong>ACTTA (Active Test-Time Augmentation)<\/strong>.<\/li>\n <li>Dezvoltarea instrumentului software A-BEACON v1.0 \u0219i a modulului de monitorizare (tracking).<\/li>\n <li>Evaluarea preliminar\u0103 clinic\u0103 (human-in-the-loop).<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Anul 3 (Luni 25-36)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Evaluare Multicentric\u0103<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Evaluarea tehnic\u0103 avansat\u0103 a algoritmului de monitorizare (tracking).<\/li>\n <li>Realizarea analizei radiomice avansate pentru evaluarea heterogenit\u0103\u021bii tumorale.<\/li>\n <li>Evalu\u0103ri clinice multicentrice \u2013 Runda 1 (Elve\u021bia) \u0219i Runda 2 (Rom\u00e2nia).<\/li>\n <li>Publica\u021bii tehnice privind cadrul ACTTA \u0219i performan\u021ba tehnic\u0103.<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Anul 4 (Luni 37-48)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Validare Final\u0103<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Evalu\u0103ri clinice multicentrice \u2013 Runda 3 (Polonia \u0219i Bulgaria).<\/li>\n <li>Finalizarea analizelor \u0219i validarea clinic\u0103 final\u0103 a sistemului A-BEACON.<\/li>\n <li>Preg\u0103tirea \u0219i publicarea rezultatelor finale clinice \u0219i tehnice.<\/li>\n <li>Eliberarea final\u0103 a software-ului A-BEACON c\u0103tre comunitatea \u0219tiin\u021bific\u0103.<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n <\/div>\n <\/section>\n\n \n <section id=\"consortiu\" class=\"mb-16 px-4 max-w-6xl mx-auto bg-white py-8 rounded-lg shadow-sm border border-slate-100 pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold text-center mb-8\">Consor\u021biul interna\u021bional<\/h2>\n <div class=\"grid grid-cols-1 sm:grid-cols-2 lg:grid-cols-4 gap-6 px-4\">\n \n <a href=\"https:\/\/www.unibe.ch\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\udde8\ud83c\udded<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">University of Bern<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Lider de proiect<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.ulbsibiu.ro\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border-b-4 border-blue-600 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\uddf7\ud83c\uddf4<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">Universitatea „Lucian Blaga” din Sibiu<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Partener clinic \u0219i tehnic<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.pib-nio.pl\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\uddf5\ud83c\uddf1<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">National Research Institute of Oncology<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Expertiz\u0103 oncologic\u0103<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.mu-varna.bg\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\udde7\ud83c\uddec<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">Medical University Varna<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Evaluare clinic\u0103<\/p>\n <\/a>\n <\/div>\n <\/section>\n\n \n <section id=\"echipa\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold mb-8\">Echipa de cercetare<\/h2>\n \n <div class=\"grid grid-cols-1 sm:grid-cols-2 md:grid-cols-4 gap-8 mb-12\">\n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/mauricio.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Mauricio+Reyes&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Mauricio Reyes\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Mauricio Reyes<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Main Applicant (CH)<\/p>\n <\/div>\n \n <div class=\"text-center p-2 bg-blue-50\/30 rounded-xl border border-blue-100 group\">\n <div class=\"w-40 h-40 bg-white mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/matei.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Claudiu+Matei&background=fff&size=256'\" alt=\"Prof. Dr. Claudiu Matei\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Claudiu Matei<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Project Manager (RO)<\/p>\n <\/div>\n \n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/kunicki.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Jacek+Kunicki&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Jacek Kunicki\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Jacek Kunicki<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Investigator (PL)<\/p>\n <\/div>\n \n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/encheva.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Elitsa+Encheva&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Elitsa Encheva\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Elitsa Encheva<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Investigator (BG)<\/p>\n <\/div>\n <\/div>\n\n <div class=\"border-t border-slate-200 pt-8\">\n <h3 class=\"text-sm font-bold text-slate-500 mb-8 text-center uppercase tracking-widest\">Echipa ULBS (Rom\u00e2nia)<\/h3>\n <div class=\"flex flex-wrap justify-center gap-10\">\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/neamtu.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Bogdan+Neamtu&background=f1f5f9&size=256'\" alt=\"Conf. Dr. Bogdan Neam\u021bu\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Conf. Dr. Bogdan Neam\u021bu<\/p>\n <p class=\"text-xs text-slate-500\">Cercet\u0103tor senior<\/p>\n <\/div>\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/sandu.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Mariana+Sandu&background=f1f5f9&size=256'\" alt=\"Dr. Mariana Sandu\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Dr. Mariana Sandu<\/p>\n <p class=\"text-xs text-slate-500\">Cercet\u0103tor<\/p>\n <\/div>\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/darius.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Darius+Peteleaza&background=f1f5f9&size=256'\" alt=\"Ing. Darius Peteleaz\u0103\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Ing. Darius Peteleaz\u0103<\/p>\n <p class=\"text-xs text-slate-500\">Asistent cercetare<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n \n <footer class=\"bg-slate-800 text-slate-300 py-10 px-4 text-center mt-12 rounded-t-lg mx-auto max-w-6xl\">\n <div class=\"max-w-2xl mx-auto\">\n <p class=\"text-sm mb-4\">Acest proiect \u00ee\u0219i propune s\u0103 \u00eembun\u0103t\u0103\u021beasc\u0103 \u00een mod semnificativ standardul de \u00eengrijire pentru pacien\u021bii cu metastaze cerebrale.<\/p>\n <p class=\"text-sm font-semibold mb-6\">Finan\u021bat de Swiss National Science Foundation (SNSF) \u0219i UEFISCDI.<\/p>\n <div class=\"w-16 h-px bg-slate-600 mx-auto mb-6\"><\/div>\n <div class=\"text-xs font-mono opacity-60\">\n © dr.ing. Radu Pascu – 2025.\n <\/div>\n <\/div>\n <\/footer>\n\n<\/div>\n\n<\/body>\n<\/html>\n","protected":false},"excerpt":{"rendered":"<p>A-BEACON – Detectare \u0219i segmentare AI a metastazelor cerebrale Despre proiect Etape Consor\u021biu Echip\u0103 \ud83c\uddf7\ud83c\uddf4 \ud83c\uddec\ud83c\udde7 \ud83c\uddeb\ud83c\uddf7 Detectare \u0219i segmentare AI a metastazelor cerebrale Proiectul A-BEACON (230215) Afl\u0103 mai multe Despre proiect Metastazele cerebrale sunt cele mai r\u0103sp\u00e2ndite neoplasme cerebrale, afect\u00e2nd unul din cinci pacien\u021bi adul\u021bi cu cancer \u0219i reprezent\u00e2nd peste jum\u0103tate din tumorile intracraniene […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-no-title","meta":{"footnotes":""},"class_list":["post-37","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/37","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/comments?post=37"}],"version-history":[{"count":15,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/37\/revisions"}],"predecessor-version":[{"id":89,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/37\/revisions\/89"}],"wp:attachment":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/media?parent=37"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

{"id":37,"date":"2025-12-11T08:06:35","date_gmt":"2025-12-11T08:06:35","guid":{"rendered":"https:\/\/grants.ulbsibiu.ro\/abeacon\/?page_id=37"},"modified":"2025-12-11T12:25:37","modified_gmt":"2025-12-11T10:25:37","slug":"a-beacon-ro","status":"publish","type":"page","link":"https:\/\/grants.ulbsibiu.ro\/abeacon\/","title":{"rendered":"A-BEACON(RO)"},"content":{"rendered":"\n\n\n\n \n \n A-BEACON – Detectare \u0219i segmentare AI a metastazelor cerebrale<\/title>\n \n \n <meta name=\"description\" content=\"Proiectul A-BEACON dezvolt\u0103 un sistem AI inovator pentru detectarea 'zero-miss' \u0219i segmentarea metastazelor cerebrale. O colaborare multicentric\u0103 \u00eentre Elve\u021bia, Rom\u00e2nia, Polonia \u0219i Bulgaria.\">\n <meta name=\"keywords\" content=\"A-BEACON, metastaze cerebrale, AI, segmentare tumori, neuro-oncologie, ACTTA, cercetare medical\u0103, ULBS, Swiss Contribution\">\n <meta name=\"author\" content=\"Echipa A-BEACON\">\n <link rel=\"canonical\" href=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/\">\n \n \n <meta property=\"og:title\" content=\"A-BEACON - Inova\u021bie \u00een detectarea metastazelor cerebrale\">\n <meta property=\"og:description\" content=\"Sistem AI pentru detectarea 'zero-miss' \u0219i urm\u0103rirea metastazelor cerebrale. Proiect finan\u021bat prin Second Swiss Contribution.\">\n <meta property=\"og:type\" content=\"website\">\n <meta property=\"og:url\" content=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/\">\n <meta property=\"og:image\" content=\"https:\/\/images.unsplash.com\/photo-1559757175-5700dde675bc?auto=format&fit=crop&q=80\">\n <meta property=\"og:locale\" content=\"ro_RO\">\n\n \n <meta name=\"twitter:card\" content=\"summary_large_image\">\n <meta name=\"twitter:title\" content=\"A-BEACON - Detectare AI metastaze cerebrale\">\n <meta name=\"twitter:description\" content=\"Sistem AI inovator pentru detectarea \u0219i segmentarea metastazelor cerebrale.\">\n <meta name=\"twitter:image\" content=\"https:\/\/images.unsplash.com\/photo-1559757175-5700dde675bc?auto=format&fit=crop&q=80\">\n \n \n <script src=\"https:\/\/cdn.tailwindcss.com\"><\/script>\n <link href=\"https:\/\/fonts.googleapis.com\/css2?family=Inter:wght@300;400;600;700;800&display=swap\" rel=\"stylesheet\">\n \n <style>\n \/* Hack pentru a ascunde titlul paginii din WordPress *\/\n .entry-title, .page-title, h1.entry-title {\n display: none !important;\n }\n\n body {\n background-color: #f8fafc;\n margin: 0;\n }\n\n #abeacon-content {\n font-family: 'Inter', sans-serif;\n color: #334155;\n line-height: 1.6;\n width: 100%;\n max-width: 100%; \n margin: 0 auto;\n background-color: #f8fafc;\n }\n \n .internal-nav {\n background: #ffffff;\n border-bottom: 1px solid #e2e8f0;\n padding: 1rem 0;\n margin-bottom: 2rem;\n position: sticky;\n top: 0;\n z-index: 40;\n }\n \n .internal-nav a {\n text-decoration: none;\n color: #475569;\n font-weight: 600;\n font-size: 0.9rem;\n margin-right: 1.5rem;\n transition: color 0.2s;\n }\n \n .internal-nav a:hover {\n color: #2563eb;\n }\n\n \/* Hero Banner Modificat *\/\n .hero-banner {\n position: relative;\n width: 100%;\n height: 500px;\n border-radius: 8px;\n overflow: hidden;\n margin-bottom: 3rem;\n box-shadow: 0 4px 6px -1px rgba(0, 0, 0, 0.1);\n background-color: #1e293b;\n }\n\n .hero-img {\n width: 100%;\n height: 100%;\n object-fit: cover;\n filter: blur(3px) brightness(0.6); \n transform: scale(1.02); \n transition: transform 0.5s ease;\n }\n \n .hero-banner:hover .hero-img {\n transform: scale(1.05);\n }\n\n .hero-text-overlay {\n position: absolute;\n top: 0;\n left: 0;\n width: 100%;\n height: 100%;\n display: flex;\n flex-direction: column;\n justify-content: center;\n align-items: flex-start;\n padding: 2rem 3rem; \n color: white;\n z-index: 10;\n }\n\n \/* Titlu Hero Mare pe Dou\u0103 R\u00e2nduri *\/\n .hero-title-large {\n font-size: 3.5rem;\n font-weight: 800;\n line-height: 1.1;\n margin-bottom: 1.5rem;\n max-width: 900px;\n text-shadow: 2px 2px 4px rgba(0,0,0,0.7);\n }\n\n @media (max-width: 768px) {\n .hero-title-large {\n font-size: 2.5rem;\n }\n .hero-text-overlay {\n padding: 1.5rem;\n }\n }\n\n \/* Steaguri *\/\n .flag-icon {\n font-size: 1.2rem;\n line-height: 1;\n cursor: pointer;\n transition: transform 0.2s;\n }\n .flag-icon:hover {\n transform: scale(1.2);\n }\n .flag-active {\n border-bottom: 2px solid #2563eb;\n padding-bottom: 2px;\n }\n\n \/* Stiluri specifice *\/\n h2 {\n color: #1e293b;\n border-left: 4px solid #2563eb;\n padding-left: 1rem;\n margin-bottom: 1.5rem;\n }\n\n \/* Smooth scroll behavior *\/\n html {\n scroll-behavior: smooth;\n }\n <\/style>\n<\/head>\n<body>\n\n<div id=\"abeacon-content\">\n\n \n <div class=\"internal-nav px-4 shadow-sm\">\n <div class=\"flex flex-col md:flex-row justify-between items-center max-w-6xl mx-auto\">\n <div class=\"flex flex-wrap justify-center md:justify-start gap-4 mb-2 md:mb-0\">\n <a href=\"#despre\">Despre proiect<\/a>\n <a href=\"#etape\">Etape<\/a>\n <a href=\"#consortiu\">Consor\u021biu<\/a>\n <a href=\"#echipa\">Echip\u0103<\/a>\n <\/div>\n \n <div class=\"flex gap-4 items-center\">\n <span class=\"flag-icon flag-active\" title=\"Rom\u00e2n\u0103\">\ud83c\uddf7\ud83c\uddf4<\/span>\n <a href=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/a-beaconen\/\" class=\"flag-icon opacity-70 hover:opacity-100\" title=\"English\">\ud83c\uddec\ud83c\udde7<\/a>\n <a href=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/a-beaconfr\/\" class=\"flag-icon opacity-70 hover:opacity-100\" title=\"Fran\u00e7ais\">\ud83c\uddeb\ud83c\uddf7<\/a>\n <\/div>\n <\/div>\n <\/div>\n\n \n <div class=\"px-4\">\n <div class=\"hero-banner max-w-6xl mx-auto\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/hero_site-scaled.png\" alt=\"Brain MRI Analysis\" class=\"hero-img\">\n <div class=\"hero-text-overlay\">\n \n <h1 class=\"hero-title-large\">\n Detectare \u0219i segmentare AI<br>\n a metastazelor cerebrale\n <\/h1>\n <p class=\"text-xl font-light opacity-90 mb-8 border-l-4 border-blue-400 pl-4 bg-black\/20 p-2 inline-block rounded backdrop-blur-sm\">\n Proiectul A-BEACON (230215)\n <\/p>\n <a href=\"#despre\" class=\"bg-blue-600 hover:bg-blue-700 text-white font-semibold py-3 px-8 rounded shadow-lg transition transform hover:-translate-y-0.5 text-lg inline-block\">Afl\u0103 mai multe<\/a>\n <\/div>\n <\/div>\n <\/div>\n\n \n <section id=\"despre\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold\">Despre proiect<\/h2>\n <div class=\"prose prose-slate max-w-none text-justify bg-white p-6 rounded-lg shadow-sm border border-slate-100\">\n <p class=\"mb-4\">\n Metastazele cerebrale sunt cele mai r\u0103sp\u00e2ndite neoplasme cerebrale, afect\u00e2nd unul din cinci pacien\u021bi adul\u021bi cu cancer \u0219i reprezent\u00e2nd peste jum\u0103tate din tumorile intracraniene la adul\u021bi. Detectarea \u0219i diagnosticarea precoce sunt cruciale, deoarece leziunile netratate pot duce la \u00eent\u00e2rzierea tratamentului, deficite neurologice grave \u0219i reducerea supravie\u021buirii globale.\n <\/p>\n <p class=\"mb-4\">\n Diagnosticul actual \u0219i planificarea tratamentului se bazeaz\u0103 \u00een mare m\u0103sur\u0103 pe imagistica prin rezonan\u021b\u0103 magnetic\u0103 (IRM), care necesit\u0103 mult\u0103 munc\u0103 \u0219i este predispus\u0103 la erori, \u00een special \u00een segmentarea manual\u0103 \u0219i urm\u0103rirea leziunilor mici \u0219i numeroase. Segmentarea manual\u0103 a metastazelor cerebrale din scan\u0103rile RMN consum\u0103 mult timp, cu variabilitate semnificativ\u0103 \u0219i probleme de sensibilitate, ceea ce duce adesea la ratarea leziunilor. Exist\u0103 o nevoie critic\u0103 nesatisf\u0103cut\u0103 de metode mai eficiente, mai precise \u0219i mai fiabile pentru a asista medicii \u00een diagnosticarea \u0219i monitorizarea acestor tumori. P\u00e2n\u0103 \u00een prezent, nu exist\u0103 nicio solu\u021bie eficient\u0103 disponibil\u0103 pentru medici.\n <\/p>\n <p class=\"mb-4\">\n Progresele recente \u00een domeniul inteligen\u021bei artificiale (AI) s-au dovedit promi\u021b\u0103toare \u00een abordarea acestor provoc\u0103ri. Modelele bazate pe IA au \u00eembun\u0103t\u0103\u021bit segmentarea \u0219i detectarea metastazelor cerebrale. Cu toate acestea, variabilitatea protocoalelor RMN, calitatea datelor \u0219i generalizarea modelelor r\u0103m\u00e2n obstacole semnificative.\n <\/p>\n \n <div class=\"mt-8 p-4 bg-blue-50 rounded border-l-4 border-blue-600\">\n <h3 class=\"font-bold text-blue-900 text-lg mb-2\">Abordare inovatoare – Cadrul A-BEACON<\/h3>\n <p class=\"text-sm text-blue-900\">\n Propunem dezvoltarea A-BEACON, un sistem bazat pe inteligen\u021b\u0103 artificial\u0103 conceput pentru a oferi detectarea „zero-miss” \u0219i urm\u0103rirea eficient\u0103 a metastazelor cerebrale. Abordarea noastr\u0103 propune metodologii \u0219i strategii inovatoare de AI pentru augmentarea activ\u0103 \u00een timpul test\u0103rii (ACTTA) \u0219i bias-uri inductive bazate pe interpretabilitate pentru a spori performan\u021ba \u0219i fiabilitatea modelului.\n Utiliz\u00e2nd un set de date multicentric de 914 cazuri reanalizate, ne vom antrena \u0219i ne vom valida modelele. Acest set de date, selectat pentru diversitatea sa \u00een ceea ce prive\u0219te caracteristicile imagistice \u0219i profilurile leziunilor, va constitui coloana vertebral\u0103 a cercet\u0103rii noastre.\n <\/p>\n <\/div>\n\n \n <div class=\"grid md:grid-cols-2 gap-6 mt-8\">\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Active Test-Time Augmentation (ACTTA)<\/h4>\n <p class=\"text-sm text-slate-700\">Aceast\u0103 nou\u0103 tehnic\u0103 va optimiza augmentarea \u00een timpul test\u0103rii pe baza corec\u021biilor utilizatorului, \u00eembun\u0103t\u0103\u021bind adaptabilitatea \u0219i performan\u021ba modelului f\u0103r\u0103 a necesita reantrenare.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Interpretability-Based Inductive Bias<\/h4>\n <p class=\"text-sm text-slate-700\">Prin \u00eencorporarea h\u0103r\u021bilor de salien\u021b\u0103 pentru a ghida antrenarea modelului, aceast\u0103 metod\u0103 vizeaz\u0103 \u00eembun\u0103t\u0103\u021birea capacit\u0103\u021bilor de detectare prin alinierea caracteristicilor modelului cu cuno\u0219tin\u021bele exper\u021bilor umani.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Urm\u0103rirea leziunilor<\/h4>\n <p class=\"text-sm text-slate-700\">Prin combinarea incertitudinilor epistemice \u0219i aleatorii, vom dezvolta metode de urm\u0103rire a leziunilor \u00een timp, diferen\u021biind metastazele noi de cele existente.<\/p>\n <\/div>\n <div class=\"bg-slate-50 p-4 rounded border border-slate-200\">\n <h4 class=\"font-bold text-blue-800 mb-2\">Integrare software (TRL-4-5)<\/h4>\n <p class=\"text-sm text-slate-700\">Un prototip de instrument software va fi dezvoltat pentru a integra aceste tehnologii, permi\u021b\u00e2nd implementarea \u0219i evalu\u0103rile clinice.<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n \n <section id=\"etape\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold\">Etapele de implementare<\/h2>\n <div class=\"space-y-6\">\n \n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Anul 1 (Luni 1-12)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Ini\u021biere<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Lansarea proiectului \u0219i angajarea echipei de cercetare.<\/li>\n <li>Achizi\u021bionarea \u0219i instalarea echipamentelor necesare.<\/li>\n <li>Recrutarea pacien\u021bilor \u0219i workshop-uri clinice pentru specificarea protocoalelor.<\/li>\n <li>Preg\u0103tirea seturilor de date: Elve\u021bia (n=200), Rom\u00e2nia (n=150), Polonia (n=150).<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Anul 2 (Luni 13-24)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Dezvoltare Tehnic\u0103<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Dezvoltarea modelelor AI de baz\u0103 pentru segmentare (benchmark cross-validation).<\/li>\n <li>Dezvoltarea encoder-ului bazat pe interpretabilitate \u0219i a variantelor TTA (Test-Time Augmentation).<\/li>\n <li>Dezvoltarea cadrului <strong>ACTTA (Active Test-Time Augmentation)<\/strong>.<\/li>\n <li>Dezvoltarea instrumentului software A-BEACON v1.0 \u0219i a modulului de monitorizare (tracking).<\/li>\n <li>Evaluarea preliminar\u0103 clinic\u0103 (human-in-the-loop).<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Anul 3 (Luni 25-36)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Evaluare Multicentric\u0103<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Evaluarea tehnic\u0103 avansat\u0103 a algoritmului de monitorizare (tracking).<\/li>\n <li>Realizarea analizei radiomice avansate pentru evaluarea heterogenit\u0103\u021bii tumorale.<\/li>\n <li>Evalu\u0103ri clinice multicentrice \u2013 Runda 1 (Elve\u021bia) \u0219i Runda 2 (Rom\u00e2nia).<\/li>\n <li>Publica\u021bii tehnice privind cadrul ACTTA \u0219i performan\u021ba tehnic\u0103.<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n \n <div class=\"bg-white rounded-lg shadow-sm border border-slate-200 overflow-hidden hover:shadow-md transition\">\n <div class=\"bg-slate-100 px-6 py-3 border-b border-slate-200 flex justify-between items-center flex-wrap gap-2\">\n <h3 class=\"font-bold text-slate-800\">Anul 4 (Luni 37-48)<\/h3>\n <span class=\"text-xs font-semibold bg-blue-100 text-blue-800 px-2 py-1 rounded\">Validare Final\u0103<\/span>\n <\/div>\n <div class=\"p-6\">\n <ul class=\"list-disc list-inside space-y-2 text-sm text-slate-700\">\n <li>Evalu\u0103ri clinice multicentrice \u2013 Runda 3 (Polonia \u0219i Bulgaria).<\/li>\n <li>Finalizarea analizelor \u0219i validarea clinic\u0103 final\u0103 a sistemului A-BEACON.<\/li>\n <li>Preg\u0103tirea \u0219i publicarea rezultatelor finale clinice \u0219i tehnice.<\/li>\n <li>Eliberarea final\u0103 a software-ului A-BEACON c\u0103tre comunitatea \u0219tiin\u021bific\u0103.<\/li>\n <\/ul>\n <\/div>\n <\/div>\n\n <\/div>\n <\/section>\n\n \n <section id=\"consortiu\" class=\"mb-16 px-4 max-w-6xl mx-auto bg-white py-8 rounded-lg shadow-sm border border-slate-100 pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold text-center mb-8\">Consor\u021biul interna\u021bional<\/h2>\n <div class=\"grid grid-cols-1 sm:grid-cols-2 lg:grid-cols-4 gap-6 px-4\">\n \n <a href=\"https:\/\/www.unibe.ch\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\udde8\ud83c\udded<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">University of Bern<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Lider de proiect<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.ulbsibiu.ro\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border-b-4 border-blue-600 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\uddf7\ud83c\uddf4<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">Universitatea „Lucian Blaga” din Sibiu<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Partener clinic \u0219i tehnic<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.pib-nio.pl\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\uddf5\ud83c\uddf1<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">National Research Institute of Oncology<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Expertiz\u0103 oncologic\u0103<\/p>\n <\/a>\n \n <a href=\"https:\/\/www.mu-varna.bg\/\" target=\"_blank\" class=\"block bg-slate-50 p-6 rounded-lg text-center hover:shadow-md transition border border-slate-200 group\">\n <div class=\"text-5xl mb-4 transform group-hover:scale-110 transition\">\ud83c\udde7\ud83c\uddec<\/div>\n <h3 class=\"font-bold text-blue-900 mb-2\">Medical University Varna<\/h3>\n <p class=\"text-xs text-slate-500 font-semibold uppercase tracking-wider\">Evaluare clinic\u0103<\/p>\n <\/a>\n <\/div>\n <\/section>\n\n \n <section id=\"echipa\" class=\"mb-16 px-4 max-w-6xl mx-auto pt-8 scroll-mt-24\">\n <h2 class=\"text-2xl font-bold mb-8\">Echipa de cercetare<\/h2>\n \n <div class=\"grid grid-cols-1 sm:grid-cols-2 md:grid-cols-4 gap-8 mb-12\">\n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/mauricio.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Mauricio+Reyes&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Mauricio Reyes\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Mauricio Reyes<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Main Applicant (CH)<\/p>\n <\/div>\n \n <div class=\"text-center p-2 bg-blue-50\/30 rounded-xl border border-blue-100 group\">\n <div class=\"w-40 h-40 bg-white mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/matei.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Claudiu+Matei&background=fff&size=256'\" alt=\"Prof. Dr. Claudiu Matei\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Claudiu Matei<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Project Manager (RO)<\/p>\n <\/div>\n \n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/kunicki.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Jacek+Kunicki&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Jacek Kunicki\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Jacek Kunicki<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Investigator (PL)<\/p>\n <\/div>\n \n <div class=\"text-center group\">\n <div class=\"w-40 h-40 bg-slate-200 mx-auto mb-4 rounded-lg overflow-hidden shadow-inner flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/encheva.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Elitsa+Encheva&background=cbd5e1&size=256'\" alt=\"Prof. Dr. Elitsa Encheva\" class=\"w-full h-full object-cover\">\n <\/div>\n <h4 class=\"font-bold text-slate-800\">Prof. Dr. Elitsa Encheva<\/h4>\n <p class=\"text-xs text-blue-600 font-semibold uppercase mt-1\">Investigator (BG)<\/p>\n <\/div>\n <\/div>\n\n <div class=\"border-t border-slate-200 pt-8\">\n <h3 class=\"text-sm font-bold text-slate-500 mb-8 text-center uppercase tracking-widest\">Echipa ULBS (Rom\u00e2nia)<\/h3>\n <div class=\"flex flex-wrap justify-center gap-10\">\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/neamtu.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Bogdan+Neamtu&background=f1f5f9&size=256'\" alt=\"Conf. Dr. Bogdan Neam\u021bu\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Conf. Dr. Bogdan Neam\u021bu<\/p>\n <p class=\"text-xs text-slate-500\">Cercet\u0103tor senior<\/p>\n <\/div>\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/sandu.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Mariana+Sandu&background=f1f5f9&size=256'\" alt=\"Dr. Mariana Sandu\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Dr. Mariana Sandu<\/p>\n <p class=\"text-xs text-slate-500\">Cercet\u0103tor<\/p>\n <\/div>\n <div class=\"text-center group\">\n <div class=\"w-32 h-32 bg-slate-100 mx-auto mb-3 rounded-lg overflow-hidden shadow-sm flex items-center justify-center transition-transform group-hover:scale-105\">\n <img decoding=\"async\" src=\"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-content\/uploads\/darius.jpg\" onerror=\"this.src='https:\/\/ui-avatars.com\/api\/?name=Darius+Peteleaza&background=f1f5f9&size=256'\" alt=\"Ing. Darius Peteleaz\u0103\" class=\"w-full h-full object-cover\">\n <\/div>\n <p class=\"font-bold text-slate-800 text-sm\">Ing. Darius Peteleaz\u0103<\/p>\n <p class=\"text-xs text-slate-500\">Asistent cercetare<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n \n <footer class=\"bg-slate-800 text-slate-300 py-10 px-4 text-center mt-12 rounded-t-lg mx-auto max-w-6xl\">\n <div class=\"max-w-2xl mx-auto\">\n <p class=\"text-sm mb-4\">Acest proiect \u00ee\u0219i propune s\u0103 \u00eembun\u0103t\u0103\u021beasc\u0103 \u00een mod semnificativ standardul de \u00eengrijire pentru pacien\u021bii cu metastaze cerebrale.<\/p>\n <p class=\"text-sm font-semibold mb-6\">Finan\u021bat de Swiss National Science Foundation (SNSF) \u0219i UEFISCDI.<\/p>\n <div class=\"w-16 h-px bg-slate-600 mx-auto mb-6\"><\/div>\n <div class=\"text-xs font-mono opacity-60\">\n © dr.ing. Radu Pascu – 2025.\n <\/div>\n <\/div>\n <\/footer>\n\n<\/div>\n\n<\/body>\n<\/html>\n","protected":false},"excerpt":{"rendered":"<p>A-BEACON – Detectare \u0219i segmentare AI a metastazelor cerebrale Despre proiect Etape Consor\u021biu Echip\u0103 \ud83c\uddf7\ud83c\uddf4 \ud83c\uddec\ud83c\udde7 \ud83c\uddeb\ud83c\uddf7 Detectare \u0219i segmentare AI a metastazelor cerebrale Proiectul A-BEACON (230215) Afl\u0103 mai multe Despre proiect Metastazele cerebrale sunt cele mai r\u0103sp\u00e2ndite neoplasme cerebrale, afect\u00e2nd unul din cinci pacien\u021bi adul\u021bi cu cancer \u0219i reprezent\u00e2nd peste jum\u0103tate din tumorile intracraniene […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-no-title","meta":{"footnotes":""},"class_list":["post-37","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/37","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/comments?post=37"}],"version-history":[{"count":15,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/37\/revisions"}],"predecessor-version":[{"id":89,"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/pages\/37\/revisions\/89"}],"wp:attachment":[{"href":"https:\/\/grants.ulbsibiu.ro\/abeacon\/wp-json\/wp\/v2\/media?parent=37"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}